Bruce Donald at ISMB

Bruce Randall Donald

William and Sue Gross Professor
      of Computer Science and Biochemistry
Duke University

Ph.D. MIT, 1987

Contact, Email, FAQ

Welcome to Bruce Donald's homepage. I am a Professor of Computer Science at Duke University and Professor of Biochemistry in the Duke University Medical Center. I'm also Director of the NIH training grant in Computational Biology and Bioinformatics.

I am a Fellow of the ACM.

My laboratory is part of the

We are grateful to our funders for their support.

You can browse my papers and books, learn about research in my laboratory, or take my (not entirely?)
Random Walk:
  1976-1980 Yale, B.A.
  1980-1984 Harvard, GSD
  1982-1987 MIT, Ph.D. in Computer Science
  1987-1998 Cornell Computer Science Department, Professor
  1994-1996 Stanford University, Sabbatical
  1995-1997 Interval Research Corporation
  1997-2006 Dartmouth, Professor
  2006-now  Duke, Professor.

Feel free to check out classes I teach, and my lab in the news.

Here are tips on using LaTeX for NIH grant applications, and seminars of interest for lab members.

I have a bit of fun stuff, including music (MP3s), MEMS movies, robot movies, and other hacks.

    For questions about the Ph.D. Program in Computational Biology or the NIH training grant please visit our FAQ or e-mail cbbdgs "at" duke "dot" edu .

    If you are interested in joining my laboratory, please read my brief FAQ.

    Contact:
    Bruce R. Donald
    Professor of Computer Science
    Professor of Biochemistry, Duke University Medical Center
    P.O. Box 90129
    Department of Computer Science
    D101 Levine Science Research Center (LSRC)
    Research Drive
    Duke University
    Durham, NC 27708-0129 USA

    Please do not send me email as quoted-printable or in HTML or base64. Just plain ASCII text. I use a text-only mail program since the graphical ones are too slow. When you get many emails a day, a couple of seconds per message matters.
    It's my initials: `b' followed by `r' followed by `d' `at' `cs' period `duke' period 'edu'.
    Phone: 919-660-6583

    Office: D212 Levine Science Research Center (LSRC)
    Please note that our lab has moved in July to great new space:
    Dry-Lab: D240 LSRC, 660-4017
    Wet-Lab: 3245, 3246, & 3248 French Family Science Center, 660-4018

    Google map; Duke Maps: LSRC, French Center

Protein Design


Computational Structure-Based Redesign of Enzyme Activity.
PNAS (2009).

Drug Design


Combatting Leukemia:
RUNX1 and CBFβ Interaction Interupted.
Chemistry & Biology (2007).

Protein Structures Gallery


Solution structure of FF Domain 2 of human transcription elongation factor CA150.
PDB ID: 2KIQ (J. Biomol. NMR 2009)

Structure of Dihydrofolate Reductase-Thymidylate Synthase from Cryptosporidium hominis.
PDB ID: 1QZF (J. Biol. Chem.)

Complete ensemble of NMR structures of the unphosphorylated human cardiac phospholamban pentamer. PDB ID: 2HYN (Proteins, 2006)

Microelectromechanical Systems


Planar Microassembly by Parallel Actuation of MEMS Microrobots. Journal of Microelectromechanical Systems (2008).