Lecture Date
Topic
Refs
   
 
1 08/26 Course Overview, Biological Background
Scribe: Pankaj Agarwal

Notes     Additional Readings
GG*
[Ch 2-4]
2 08/28 Biological Background, Computation Intro
Scribe: Pankaj Agarwal

Notes     Additional Readings     
GG*
   
 
3 09/02

Mathematical Foundation, Model of Computation
Scribe: Leelavati Narlikar

Notes       

CLR
[Ch 1-3]
4 09/04 Divide and conquer, Greedy Algorithms
Scribe: Leelavati Narlikar

Notes    
CLR
[Ch 1, 4]
5 09/09 Dynamic Programing
Scribe: David Vaughn

Notes    
CLR
[Ch 16,17]
6 09/11 Graphs, Representation of Graphs, Traversal Algorithms
Scribe: Sukhendu Chakraborty

Notes      Homework 1
CLR
[Ch 23]
7 09/16 Minimum Spanning Trees, Shortest Paths
Guest Lecturer: Yusu Wang
Scribe: Joe Volpe

Notes     Readings
CLR
[Ch 24,25]
  09/18 No Class  
   
 
8 09/23 Sequence Alignment I: Global Alignment
Scribe: Avik Bhattacharya

Notes     Readings
M [Ch 3]
P
9 09/25 Sequence Alignment II: Global and Semiglobal Alignment
Scribe: Jeff Phillips

Notes     Readings
M [Ch 3]
P
10 09/30 Local Alignment and Substitution Matrices
Scribe: Madhuwanti Vaidya

Notes     Homework 2
P
EG
SM
11 10/02 Sequence Database Search: BLAST and FASTA
Scribe: Dmitri Morozov

Notes     Readings
EG
SM
   
 
12 10/07 Genome Assembly
Scribe: Philippe Luedi

Notes     Readings
SM
W
13 10/09 Probabilistic and Stochastic Modeling
Scribe: Tingting Jiang

Notes     Readings
DE*
[Ch 11]
EG
  10/14 Fall Break  
14 10/16 Hidden Markov Models (Guest Lecture)
Guest Lecturer: Ron Parr
Scribe: Wenbin Pan

Slides      Notes     Readings
DE* [Ch 3]
15 10/21 Multiple Sequence Alignment
Scribe: David Orlando

Notes     Readings
DE*
[Ch 5,6]
M
16 10/23 Profile HMM and multiple alignment
Scribe: Sarah Roberts

Notes     Readings
P
M [Ch 8]
   
 
17 10/28 Gene Prediction
Scribe: Haige Shen

Notes     Homework 3
 
18 10/30 Analyzing Gene Expression Data: Clustering & classification
Scribe: Dajun Hou

Notes     Readings
 
   
 
19 11/04 Proteins, Primary Strucure
Scribe:
Quihua Liu

Notes     Readings
L
BT
20 11/06 Secondary Structure Prediction
Scribe: Jeff Headd

Notes     Readings
L
St
21 11/11 Tertiary Strucure (Guest Lecture)
Guest Lecturer: Leelavati Narlikar
Scribe: Curtis Layton

Notes     Readings
L
St
22 11/13 Space Filling Diagrams
Scribe: Pankaj Agarwal

Notes     Readings
 
23 11/18 Shape Analysis
Scribe:Pankaj Agarwal

Notes     Readings
 
   
 
24 11/20 Protein Folding
 
25 11/25 Protein-Protein Interaction
Scribe: Li Liu

Notes     Readings
 
26 and 27 12/02 and 12/04 Project Presentations

Schedule