Advanced Topics: BioNanoTechnology (CPS296.05)



EVOLVING LECTURE SCHEDULE

Th.Jan.12 Class Introduction and Overview: Books, Class Projects, Lectures, Webpages, Introduce: Smalley vs Drexler, Slides PDF.
Tu.Jan.17 Overview of Nanotechnology: Feynman, Drexler, Smalley vs Drexler Debate STM mechanical chemistry, Slides PDF.
Th.Jan.19 Structural Principles: Molecular SA Nanochemistry, Self-organization, Overview of Self-assembly, Rothemund Mesoscale Self-assembly.
Tu.Jan.24 Structural Principles: II, Self assembly, Install Kinemage, KiNG software.
Th.Jan.26 Biomolecular Structure: ( DNA, RNA, Proteins), Slides PDF.
Tu.Jan.31 Biomolecular Structure: (DNA, RNA, Proteins), Slides PDF.
Th.Feb.2 Biomolecular Structure: (RNA, Proteins)
Tu.Feb.7 Biomolecular Structure: (Proteins), Evidence of folding in arbitrary sequence proteins. De novo design: Alpha-4, designed hydrophobic cores FELIX, Folding sequences from binary patterned combinatorial library , Stable designed protein Top7, Re-engineered function , Slides PDF.
Th.Feb.9 Biomolecular Structure: (Lipids, liposomes, carbohydrate, other), Slides PDF.
Tu.Feb.14 Biomolecular Structure: Protein molecular motors. Kinesin 1, 2. ATP Synthase 1, 2. Other: Flagellum , Slides PDF.
Th.Feb.16 Methods. Tools. Instrumentation: STM, Scanning Probe Microscopies, TEM EDXS, EM EELS, Slides PDF.
Tu.Feb.21 NanoStructured Materials Intro. Slides PDF.
Th.Feb.23 NanoStructured Materials: Carbon Nanotubes, Carbon nanotube biosensors, DNA and SWCNT, DNA bond SWCNT for separation, Carbon nanotube transistor, Carbon nanotube devices, Carbon nanotube circuits, CNT targeted deposition, SWCNT surface patterning, CNT bibliography, Slides PDF.
Tu.Feb.28 NanoStructured Materials: NanoParticles, NanoParticle Arrays, NanoWires, Silicon nanowire synthesis,Silicon nanowire contacts, Silicon nanowire doping, SiNW devices, SiNW circuits. Nanoparticles. NanoParticles, NanoParticle DNA Conjugates, DNA & Protein directed NanoParticle Assembly, TAE tile linear assembler, Slides PDF.
Th.Mar.2 DNA Self-Assembly: Seeman's views of DNA-based Nanofabrication 1999, 2001, 2003, DNA-based Computing and Nanofabrication, Early Seeman Lab work, 2D DNA crystals (DX), TX Lattice, TX Tubes and Wires, 4x4 Lattice & Tubes , Slides PDF.
Tu.Mar.7 DNA Self-Assembly: Barcode Lattice, Parallelogram tiles, TAE linear arrays, Random DNA Networks, Cloned octahedron DNA Templating: DNA templating for nanoelectronics, DNA Templated Ag Nanowire, DNA molecular lithography, DNA/Au + CNT FET, 4x4 tube templates, TAO tube templates, DNA templated nanowires of: palladium, platinum, gold, copper, Slides PDF.
Th.Mar.9 DNA-based Computing: Adleman's original experiment, Landweber Review, DNA Algorithmic Assembly XOR self-assembly, Parallel string tile XOR.... 20 Variable 3-SAT,Hairpin DNA computer, RNA computer, Surface computer I, Surface computer II ... Autonomous computing machine I, Autonomous computing machine II, DNA molecular logic gates , Tictactoe DNA automaton , Tictactoe news & views , DNA Steganography, Slides PDF.
Tu.Mar.14 SPRING BREAK (no meeting)
Th.Mar.16 SPRING BREAK (no meeting)
Tu.Mar.21 DNA Actuators & Robotics, DNA fueled DNA machine, DNA Nanoactuator, Motor Lattice, BZ device, PX-JX device, Slides PDF.
Th.Mar.23 RNA Selection, Evolution, Engineering, Self-Assembly: RNA In vitro Evolution: Tuerk & Gold, Ellington & Szostak, Bartel & Szostak, NA selection review, Neutral path, L. Jaeger RNA Self-assembly, Protein In vitro Evolution: M13 Phage display, Peptide ligands by library methods , Sexual PCR, Gene shuffling, Stemmer review, Slides PDF.
Tu.Mar.28 BioNanoTech with Viruses: Filamentous phage and semiconductors, and Quantum dot assembly, as nanotool box , Icosohedral phage: 1 , Slides PDF.
Th.Mar.30 Protein BioNano. S-layers, Nucleoprotein Assemblies Review, self-assembled protein networks, Peptide templates for nanowires, Chaperonin organized nanoparticles, Designed fusion protein assemblies, Switchable Protein Surfaces , Review , Protein/CNT Biosensor, others, Slides PDF.
Tu.Apr.4 Biomineralization. Ceramics & semiconductors , On peptide templates , Biocatalytically formed silica, Diatoms (1), Diatoms (2) , Biopeptides for silica templating 1, 2, Slides PDF.
Th.Apr.6 Molecular Electronics. Phil Ball NanoComputing Review, Review of Molecular Electronics, Molecular electronics overview, ME Reed-Tour. Sci Am., Molecular switches, Better molecular switches , Tunable Quantum Dots, Templated nanowire patterning, Directed Assembly of NW Arrays. Quantum Cellular Automata QCA Review, Slides PDF.
Tu.Apr.11 TBA
Th.Apr.13 Finish topics. Jeopardy review.
Tu.Apr.18 Lab tour: AFM, TEM, SEM
Other Useful Things Periodic Table of Elements
Other Things to Cover Given Time Tie-ins, etc. Electrically assembled microwires from nanoparticles, sequence specific DNA helix angles,



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