BioNanoTechnology (CPS296.04 / NANO 316)



LECTURE SCHEDULE

Tu.Jan.15 Class Introduction Books, Class Projects, Lectures, Webpages. Overview of Nanotechnology: Feynman, Drexler, Smalley vs Drexler Debate STM mechanical chemistry, Bio-Inspiration, Slides PDF.
Tu.Jan.22 Self-Assembly Molecular SA: Nanochemistry, Self-organization, Overview of Self-assembly, Rothemund Mesoscale Self-assembly, Slides PDF.
Tu.Jan.29 Biomolecular Structure Install Kinemage, KiNG software, ( DNA, RNA, Proteins), Slides PDF.
Tu.Feb.5 Biomolecular Structure (Proteins), Evidence of folding in arbitrary sequence proteins. De novo design: Alpha-4, designed hydrophobic cores FELIX, Folding sequences from binary patterned combinatorial library , Stable designed protein Top7, Re-engineered function , Other Biomolecular Structure: (Lipids, liposomes, carbohydrate, other), Slides PDF.
Tu.Feb.12 Protein molecular motors Kinesin 1, 2. ATP Synthase 1, 2. Other: Flagellum , Slides PDF.
Tu.Feb.19 Nano Tools & Materials Tools. Instrumentation: STM, Scanning Probe Microscopies, TEM EDXS, EM EELS, NanoStructured Materials: Carbon Nanotubes, Carbon nanotube biosensors, DNA and SWCNT, DNA bond SWCNT for separation, Carbon nanotube transistor, Carbon nanotube devices, Carbon nanotube circuits, CNT targeted deposition, SWCNT surface patterning, CNT bibliography, NanoParticles, NanoParticle Arrays, NanoWires, Silicon nanowire synthesis,Silicon nanowire contacts, Silicon nanowire doping, SiNW devices, SiNW circuits. Nanoparticles. NanoParticles, NanoParticle DNA Conjugates, DNA & Protein directed NanoParticle Assembly, TAE tile linear assembler, Slides PDF.
Tu.Feb.26 DNA Self-Assembly & Computing Seeman's views of DNA-based Nanofabrication 1999, 2001, 2003, DNA-based Computing and Nanofabrication, Early Seeman Lab work, 2D DNA crystals (DX), TX Lattice, TX Tubes and Wires, 4x4 Lattice & Tubes, Barcode Lattice, Parallelogram tiles, TAE linear arrays, Random DNA Networks, Cloned octahedron DNA Templating: DNA templating for nanoelectronics, DNA Templated Ag Nanowire, DNA molecular lithography, DNA/Au + CNT FET, 4x4 tube templates, TAO tube templates, DNA-based Computing: Adleman's original experiment, Landweber Review, DNA Algorithmic Assembly XOR self-assembly, Parallel string tile XOR.... 20 Variable 3-SAT,Hairpin DNA computer, RNA computer, Surface computer I, Surface computer II ... Autonomous computing machine I, Autonomous computing machine II, DNA molecular logic gates , Tictactoe DNA automaton , Tictactoe news & views , DNA Steganography, Slides PDF.
Tu.Mar.4 DNA Actuators & Robotics DNA fueled DNA machine, DNA Nanoactuator, Motor Lattice, BZ device, PX-JX device, Slides PDF.
Tu.Mar.11 Spring Break (no meeting)
Tu.Mar.18 RNA Assembly & Evolution RNA In vitro Evolution: Tuerk & Gold, Ellington & Szostak, Bartel & Szostak, NA selection review, Neutral path, L. Jaeger RNA Self-assembly, Protein In vitro Evolution: M13 Phage display, Peptide ligands by library methods , Sexual PCR, Gene shuffling, Stemmer review, Slides PDF.
Tu.Mar.25 Virus & Protein Assemblies Filamentous phage and semiconductors, and Quantum dot assembly, as nanotool box , Icosohedral phage: 1 , Protein BioNano. S-layers, Nucleoprotein Assemblies Review, self-assembled protein networks, Peptide templates for nanowires, Chaperonin organized nanoparticles, Designed fusion protein assemblies, Switchable Protein Surfaces , Review , Protein/CNT Biosensor, others, Slides PDF.
Tu.Apr.1 Biomineralization Ceramics & semiconductors , On peptide templates , Biocatalytically formed silica, Diatoms (1), Diatoms (2) , Biopeptides for silica templating 1, 2, Slides PDF.
Tu.Apr.8 Molecular Electronics. Phil Ball NanoComputing Review, Review of Molecular Electronics, Molecular electronics overview, ME Reed-Tour. Sci Am., Molecular switches, Better molecular switches , Tunable Quantum Dots, Templated nanowire patterning, Directed Assembly of NW Arrays. Quantum Cellular Automata QCA Review, Slides PDF.
Tu.Apr.15 Finish topics. AFM. Jeopardy review.



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