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Lectures

Lectures

  1. Introduction to the Course
  2. Big Questions in Drug Design and Computational Modeling
  3. Protein Backbone Geometry
  4. PyMOL Demo
  5. Nucler Magnetic Resonance: Introduction to NOESY and Chemical shifts
  6. KiNG Demo
  7. Nuclear Magnetic Resonance: HSQC, HNHA
  8. JIGSAW Algorithm: Slides
  9. JIGSAW and Core-Binding Factor Beta
  10. Dead-End Elimination and Protein Design: Mayo Paper
  11. Dead-End Elimination Continued
  12. Anticipating Resistance
  13. A* Search: Slides
  14. Drug Design: An Example of Core-Binding Factor Beta: Slides
  15. K* Algorithm
  16. Basic Physics for RDCs: Notes
  17. Residual Diploar Coupling
  18. RDCs and Structure Determination Slides
  19. Project Presentations. 03/30-4/22
  20. Designing an AIDS vaccine. Readings

Lecture Pictures

January 14, 2011
January 26, 2011
January 28, 2011
February 04, 2011
February 09, 2011