Publications
- Robinson, J. & Hartemink, A. (2008) “Non-Stationary Dynamic Bayesian Networks.” Neural Information Processing Systems 2008 (NIPS08), (accepted).
- Orlando, D., Lin, C., Bernard, A., Wang, J., Socolar, J., Iversen, E., Hartemink, A., & Haase, S. (2008) “Global Control of Cell-Cycle Transcription by Coupled CDK and Network Oscillators.” Nature, 453, 12 June 2008. pp. 944–947. [Supp. Info.]
- Gordân, R., Narlikar, L., & Hartemink, A. (2008) “A Fast, Alignment-Free, Conservation-Based Method for Transcription Factor Binding Site Discovery.” Research in Computational Molecular Biology 2008 (RECOMB08). Lecture Notes in Bioinformatics, Vingron, M. & Wong, L., eds. 4955, April 2008. pp. 98–111. [Supp. Info.]
- Gordân, R. & Hartemink, A. (2008) “Using DNA Duplex Stability Information for Transcription Factor Binding Site Discovery.” In Pacific Symposium on Biocomputing 2008 (PSB08), Altman, R., Dunker, A.K., Hunter, L., Murray, T., & Klein, T., eds. World Scientific: New Jersey. pp. 453–464. [Supp. Info.]
- Lüdi, P., Dietrich, F., Weidman, J., Bosko, J., Jirtle, R., & Hartemink, A. (2007) “Computational and Experimental Identification of Novel Human Imprinted Genes.” Genome Research, 17, December 2007. pp. 1723–1730. [Supp. Info.] [Cover] [Nature Reviews Genetics] [Science] [AP] [Wired]
- Narlikar, L., Gordân, R., & Hartemink, A. (2007) “A Nucleosome-Guided Map of Transcription Factor Binding Sites in Yeast.” PLoS Computational Biology, 3, November 2007. pp. 2199–2208.
- Bernard, A., Vaughn, D., & Hartemink, A. (2007) “Reconstructing the Topology of Protein Complexes.” Research in Computational Molecular Biology 2007 (RECOMB07). Lecture Notes in Bioinformatics, Speed, T. & Huang, H., eds. 4453, April 2007. pp. 32–46.
- Narlikar, L., Gordân, R., & Hartemink, A. (2007) “Nucleosome Occupancy Information Improves de novo Motif Discovery.” Research in Computational Molecular Biology 2007 (RECOMB07). Lecture Notes in Bioinformatics, Speed, T. & Huang, H., eds. 4453, April 2007. pp. 107–121. [Supp. Info.]
- Orlando, D., Lin, C., Bernard, A., Iversen, E., Hartemink, A., & Haase, S. (2007) “A Probabilistic Model for Cell Cycle Distributions in Synchrony Experiments.” RECOMB Satellite Conference on Systems Biology 2006, Cell Cycle, 6, February 2007. pp. 478–488.
- Smith, V., Yu, J., Smulders, T., Hartemink, A., & Jarvis, E. (2006) “Computational Inference of Neural Information Flow Networks.” PLoS Computational Biology, 2, November 2006. pp. 1436–1449. [Supp. Info.] [Code] [Most Viewed Research Article at PLoS Computational Biology]
- Bernard, A. & Hartemink, A. (2006) “Evaluating Algorithms for Learning Biological Networks.” DREAM Workshop, September 2006.
- Narlikar, L., Gordân, R., Ohler, U., & Hartemink, A. (2006) “Informative Priors Based on Transcription Factor Structural Class Improve de novo Motif Discovery.” Intelligent Systems in Molecular Biology 2006 (ISMB06), Bioinformatics, 22, July 2006. pp. e384–e392. [Supp. Info.] [Code] [Input Data]
- Hartemink, A. (2006) “Bayesian Networks and Informative Priors: Transcriptional Regulatory Network Models.” In Bayesian Inference for Gene Expression and Proteomics, Do, K.-A., Müller, P., & Vannucci, M., eds. Cambridge University Press: Cambridge, UK. pp. 401–424.
- Narlikar, L. & Hartemink, A. (2006) “Sequence Features of DNA Binding Sites Reveal Structural Class of Associated Transcription Factor.” Bioinformatics, 22, January 2006. pp. 157–163.
- Pratapa, P., Patz, E., & Hartemink, A. (2006) “Finding Diagnostic Biomarkers in Proteomic Spectra.” In Pacific Symposium on Biocomputing 2006 (PSB06), Altman, R., Dunker, A.K., Hunter, L., Murray, T., & Klein, T., eds. World Scientific: New Jersey. pp. 279–290. [Larger Figs.]
- Krishnapuram, B., Williams, D., Xue, Y., Carin, L., Figueiredo, M., & Hartemink, A. (2005) “Active Learning of Features and Labels.” Learning with Multiple Views Workshop at ICML05, August 2005.
- Lüdi, P., Hartemink, A., & Jirtle, R. (2005) “Genome-wide Prediction of Imprinted Murine Genes.” Genome Research, 15, June 2005. pp. 875–884.
- Krishnapuram, B., Figueiredo, M., Carin, L., & Hartemink, A. (2005) “Sparse Multinomial Logistic Regression: Fast Algorithms and Generalization Bounds.” IEEE Transactions on Pattern Analysis and Machine Intelligence (PAMI), 27, June 2005. pp. 957–968. [Code]
- Hartemink, A. (2005) “Reverse Engineering Gene Regulatory Networks.” Nature Biotechnology, 23, May 2005. pp. 554–555.
- Yin, P. & Hartemink, A. (2005) “Theoretical and Practical Advances in Genome Halving.” Bioinformatics, 21, April 2005. pp. 869–879.
- Bernard, A. & Hartemink, A. (2005) “Informative Structure Priors: Joint Learning of Dynamic Regulatory Networks from Multiple Types of Data.” In Pacific Symposium on Biocomputing 2005 (PSB05), Altman, R., Dunker, A.K., Hunter, L., Jung, T., & Klein, T., eds. World Scientific: New Jersey. pp. 459–470. [Supp. Info.]
- Krishnapuram, B., Williams, D., Xue, Y., Hartemink, A., Carin, L., & Figueiredo, M. (2005) “On Semi-Supervised Classification.” In Advances in Neural Information Processing Systems 17 (NIPS04), Saul, L., Weiss, Y., & Bottou, L., eds. MIT Press: Cambridge, MA. pp. 721–728.
- Yu, J., Smith, V., Wang, P., Hartemink, A., & Jarvis, E. (2004) “Advances to Bayesian Network Inference for Generating Causal Networks from Observational Biological Data.” Bioinformatics, 20, December 2004. pp. 3594–3603.
- Krishnapuram, B., Hartemink, A., Carin, L., & Figueiredo, M. (2004) “A Bayesian Approach to Joint Feature Selection and Classifier Design.” IEEE Transactions on Pattern Analysis and Machine Intelligence (PAMI), 26, September 2004. pp. 1105–1111.
- Krishnapuram, B., Carin, L., & Hartemink, A. (2004) “Joint Classifier and Feature Optimization for Comprehensive Cancer Diagnosis Using Gene Expression Data.” Journal of Computational Biology, 11, March 2004. pp. 227–242.
- Krishnapuram, B., Carin, L., & Hartemink, A. (2004) “Gene Expression Analysis: Joint Feature Selection and Classifier Design.” In Kernel Methods in Computational Biology, Schölkopf, B., Tsuda, K., & Vert, J.-P., eds. MIT Press: Cambridge, MA. pp. 299–318.
- Liu, Q., Krishnapuram, B., Pratapa, P., Liao, X., Hartemink, A., & Carin, L. (2003) “Identification of Differentially Expressed Proteins Using MALDI-TOF Mass Spectra.” ASILOMAR Conference: Biological Aspects of Signal Processing, November 2003.
- Krishnapuram, B., Carin, L., & Hartemink, A. (2003) “Joint Classifier and Kernel Design.” Kernel Methods in Bioinformatics Workshop at RECOMB03, April 2003.
- Krishnapuram, B., Carin, L., & Hartemink, A. (2003) “Joint Classifier and Feature Optimization for Cancer Diagnosis Using Gene Expression Data.” Research in Computational Molecular Biology 2003 (RECOMB03), April 2003.
- Smith, V., Jarvis, E., & Hartemink, A. (2003) “Influence of Topology and Data Collection on Functional Network Inference.” In Pacific Symposium on Biocomputing 2003 (PSB03), Altman, R., Dunker, A.K., Hunter, L., Jung, T., & Klein, T., eds. World Scientific: New Jersey. pp. 164–175.
- Yu, J., Smith, V., Wang, P., Hartemink, A., & Jarvis, E. (2002) “Using Bayesian Network Inference Algorithms to Recover Molecular Genetic Regulatory Networks.” International Conference on Systems Biology 2002 (ICSB02), December 2002.
- Jarvis, E., Smith, V., Wada, K., Rivas, M., McElroy, M., Smulders, T., Carninci, P., Hayashisaki, Y., Dietrich, F., Wu, X., McConnell, P., Yu, J., Wang, P., Hartemink, A., & Lin, S. (2002) “A Framework for Integrating the Songbird Brain.” Journal of Comparative Physiology A, 188, December 2002. pp. 961–980.
- Krishnapuram, B., Hartemink, A., & Carin, L. (2002) “Applying Logistic Regression and RVM to Achieve Accurate Probabilistic Cancer Diagnosis from Gene Expression Profiles.” GENSIPS: Workshop on Genomic Signal Processing and Statistics, October 2002.
- Smith, V., Jarvis, E., & Hartemink, A. (2002) “Evaluating Functional Network Inference Using Simulations of Complex Biological Systems.” Intelligent Systems in Molecular Biology 2002 (ISMB02), Bioinformatics, 18:S1. pp. S216–S224.
- Hartemink, A., Gifford, D., Jaakkola, T., & Young, R. (2002) “Bayesian Methods for Elucidating Genetic Regulatory Networks.” IEEE Intelligent Systems, special issue on Intelligent Systems in Biology, 17, March/April 2002. pp. 37–43.
- Hartemink, A., Gifford, D., Jaakkola, T., & Young, R. (2002) “Combining Location and Expression Data for Principled Discovery of Genetic Regulatory Networks.” In Pacific Symposium on Biocomputing 2002 (PSB02), Altman, R., Dunker, A.K., Hunter, L., Lauderdale, K., & Klein, T., eds. World Scientific: New Jersey. pp. 437–449.
- Hartemink, A. (2001) “Principled Computational Methods for the Validation and Discovery of Genetic Regulatory Networks.” Massachusetts Institute of Technology, Ph.D. dissertation.
- Hartemink, A., Gifford, D., Jaakkola, T., & Young, R. (2001) “Maximum Likelihood Estimation of Optimal Scaling Factors for Expression Array Normalization.” SPIE International Symposium on Biomedical Optics 2001 (BiOS01). In Microarrays: Optical Technologies and Informatics, Bittner, M., Chen, Y., Dorsel, A., & Dougherty, E., eds. Proceedings of SPIE, 4266. pp. 132–140.
- Hartemink, A., Gifford, D., Jaakkola, T., & Young, R. (2001) “Using Graphical Models and Genomic Expression Data to Statistically Validate Models of Genetic Regulatory Networks.” In Pacific Symposium on Biocomputing 2001 (PSB01), Altman, R., Dunker, A.K., Hunter, L., Lauderdale, K., & Klein, T., eds. World Scientific: New Jersey. pp. 422–433.
- Hartemink, A., Mikkelsen, T., & Gifford, D. (2000) “Simulating Biological Reactions: A Modular Approach.” DNA Based Computers V. Winfree, E. & Gifford, D., eds. DIMACS Series in Discrete Mathematics and Theoretical Computer Science, 54, American Mathematical Society. pp. 111–121.
- Schechter, S., Parnell, T., & Hartemink, A. (1999) “Anonymous Authentication of Membership in Dynamic Groups.” Financial Cryptography '99. Franklin, M., ed. Lecture Notes in Computer Science, 1648, Springer-Verlag. pp. 184–195.
- Hartemink, A., Gifford, D., & Khodor, J. (1999) “Automated Constraint-Based Nucleotide Sequence Selection for DNA Computation.” Biosystems, 52, October 1999, Elsevier Press. pp. 227–235.
- Hartemink, A. & Gifford, D. (1999) “Thermodynamic Simulation of Deoxyoligonucleotide Hybridization for DNA Computation.” DNA Based Computers III. Rubin, H. & Wood, D., eds. DIMACS Series in Discrete Mathematics and Theoretical Computer Science, 48, American Mathematical Society. pp. 25–38.